May 23, 2021 · Long-term survival data in relation to sub-sites, human papillomavirus (HPV), and p16^INK4a (p16) for patients with oropharyngeal squamous cell carcinoma (OPSCC) is still sparse. Furthermore, reports have indicated atypical and late recurrences for patients with HPV and p16 positive OPSCC. … Jun 15, 2022 · Objective To evaluate whether the presence of human papillomavirus (HPV) DNA and p16 might be associated with better prognosis in patients with hypopharyngeal carcinoma (HPC), especially on overall survival (OS) and disease-free survival (DFS). Method PubMed, the Cochrane Library, the Web of Science and EMBASE were searched from inception to April 2021 to search for HPV DNA- and p16-related Dec 18, 2017 · Context. Human papillomavirus (HPV) is a major cause of oropharyngeal squamous cell carcinomas, and HPV (and/or surrogate marker p16) status has emerged as a prognostic marker that significantly impacts clinical management. There is no current consensus on when to test oropharyngeal squamous cell carcinomas for HPV/p16 or on which tests to choose.Objective. To develop evidence-based Oct 1, 2014 · We demonstrated that p16 is positive in the vast majority of patients with anal cancer, and there is good correlation of these different methods used to determine HPV tumor status. These results also support the measurement of p16 as a surrogate marker for HPV infection, using the readily available and relatively inexpensive conventional IHC Jun 14, 2022 · P16-positive NPCs have a tendency of better PFS than p16-negative NPCs. This better prognosis might be due to good radiosensitivity of p16-positive cell. Additionally, there seems to exist a difference in the pattern of tumor spread in circumference along the nasopharyngeal mucosa between p16-positive and -negative NPCs. Jun 14, 2022 · There were two p16-positive patients among the keratinizing NPCs.The mean circumferential tumor extent scores of 16-positive and p16-negative NPCs were 4.2 and 3.2, respectively with a .

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